Genetic Variation (GV)

COST-Legend (2018-2022): The European Union-funded COST Action (LEukaemia GENe Discovery by data sharing, mining, and collaboration – LEGEND)

An international and multidisciplinary collaboration between clinicians and researchers that covered a range of aspects of genetic predisposition in childhood leukemia

'Origin': I-BFM ALL Host Genetic Variation Working Group

Coordinated by Christian Peter Kratz, Martin Stanulla, Hélène Cavé

Coordination with the SIOPE-Host Genome group

Introduction of easy tools to recognize leukemia predisposition in different clinical protocol: by several members

Two editions (2019, 2021) of the ‘Predisposition to hereditary Leukemia and Lymphoma Training School” (COST-Action)

Cohesin genes variants in ALL

G. Cazzaniga (IT), J. Hauer (DE)

ELEGANT Study (Exploring Leukemia: Education, Genetics, And Novel Technologies)

K. Schmiegelow (DK)

Family-based analysis of germline variants of children with leukemia/lymphoma

Lymphoid malignancies in children with AT

Sarah Elitzur (IL)

Mono- and digenic germline predisposition in BCP-ALL

F.Auer, J.Hauer, A.Borkhardt (DE) and others

Mutational patterns in tumors of children with NBS and AT

Dilys Weijers (NL)